Studies on previous strains of coronavirus have demonstrated that healthy individuals with no history of olfactory dysfunction can develop anosmia after exposure to the virus.13 A recent study demonstrated that, within the respiratory tract, the nasal respiratory epithelium has the highest expression of SARS-CoV-2 entry genes.4 A study in 2008 on transgenic mice for the SARS-CoV receptor, angiotensin-converting enzyme 2, found that the entry point for brain infections was the olfactory bulb. This evidence concerns the gene ACE2 and Kallmann syndrome.