Using logistic regression, we found negative associations for vitamin D insufficiency and VDR gene for 6 SNV’s (rs7967152, rs9729, rs739837, rs11168287, rs7963776 and rs4237855) and in CYP24A1 for 2 SNVs (rs4809960 and rs2245153), which means that the presence of above variants reduce the possibility of a certain individual to be insufficient for 25(OH)D serum levels. Here, CYP24A1 is linked to vitamin D deficiency.