TGFB1 and asthma: The manifestation of asthma is also brought about by the concerted effects of numerous pathways and large regulatory networks, such as the transforming growth factor β (TGF-β)/Smad signaling pathway [2], STAT3/NF-κB signaling pathway [3], IL-37 signaling pathway [4], Notch1-GATA3 signaling pathway [5], and many others [6–9].