GPT and obesity due to melanocortin 4 receptor deficiency: We examined whether the RIAO level was tagged with clinical-biochemical profiles (waist/size ratio, SBP and DBP centile, C-peptide in fasting, HOMA, QUICKI, TG, C-HDL, C-NoHDL, UA, ALT, and exercise) using data-driven cluster analysis; 3 clusters were obtained whose profiles could be typified as “healthy” obesity (cluster 1), gynecoid obesity (cluster 2), and android obesity (cluster 3) (Fig 8).