Histone deacetylase 6 (HDAC6), originally known as a member of class IIb histone deacetylases family, implicated in multiple cellular processes related to cancer including carcinogenesis, tumor formation, cell adhesion, oncogenic transformation, motility, DNA damage response, cell survival, chaperone function, tumor aggressiveness, stress response, and anchorage-independent proliferation [6, 7]. The gene discussed is HDAC6; the disease is neoplasm.