MTHFD2 and meningioma: Subsequently, a TF-miRNA-target gene coregulation network was constructed to study the potential molecular mechanisms, and the top 20 nodes ranked by degree were identified, including 1 TF (NF-κB), 4 miRNAs (hsa-miR-574-5p, hsa-miR-26b-5p, hsa-miR-335-5p, and hsa-miR-98-5p), and 15 key genes (IL6, CHRDL1, PTGS2, MTHFD2, SLC7A11, ADM, CRISPLD2, ROBO1, FHL2, SLC7A5, MYC, FOSL1, PLLP, HIF1A, and NAV2), which may play significant roles in meningioma.