CD4 and neoplasm: First, the population of leukocytes (CD45+) continuously increased, indicating the improvement of tumor inflammation after the treatment (Figure 4c).[[qv: 53]] Tumor infiltrated CD8+ T cells (gating on Live CD45+CD3+CD4‐CD8+; Figure S17, Supporting Information), the direct evidence of systemic immunity,[[qv: 22]] were examined at 3rd, 7th, and 14th day after the primary tumors were subjected to phototherapies (Figure 4d).