TGFB2 and esophageal squamous cell carcinoma: Another tissue microarray consisting of 40 primary ESCC tumors and matched metastatic tissues was further used to detect TGFβ2 expression, and the immunohistochemistry data showed that the majority of the metastatic tumor tissues had higher TGFβ2 expression than the corresponding primary tumors (Figure 1G,H), corroborating our findings above that high TGFβ2 expression is correlated with metastasis and poor prognosis.