Kaplan–Meier survival analysis showed that the patients with high p‐CREB1 expression in their tumors had significantly shorter survival (median survival = 13.0 months) than the patients with low tumor p‐CREB1 expression (median survival = 26.0 months) (log‐rank = 13.28, P < 0.001, Figure 6B). Here, CREB1 is linked to neoplasm.