MAPT and Alzheimer disease: Recently, Angeloni et al. analysed the relationship between oleocanthal and AD suggesting that, besides its effects to interfere with tau protein hyperphosphorylation and aggregation and its ability to induce Aβ efflux and clearance, it might counteract AD's progression by reducing glycation in the brain, thanks to its positive effect on the GSH level, and to its ability to decrease oxidative stress [241].