After adjusting for age, gender, BMI, SBP, DBP, smoking (yes/no), drinking (yes/no), the number of topical glaucoma medications, and IOP, the analyses revealed that TAS (OR = 0.773, 95%CI = 0.349–0.714, p < 0.001), SOD (OR = 0.975, 95%CI = 0.955–0.995, p < 0.001), MDA (OR = 1.155, 95%CI = 1.080–1.235, p < 0.001), and H2O2 (OR = 1.216, 95%CI = 1.142–1.295, p < 0.001) were independent risk/protective factors for PACG. Here, SOD1 is linked to glaucoma.