AA: p = 0.035, OR = 0.704, 95% CI: 0.508-0.975) [18, 19, 25, 29] .The heterogeneity test for the pooled data sets was not significant (I2 = 0) for the TLR-2 rs1898830 polymorphism in five gene models, indicating the robustness of the meta-analysis for chronic periodontitis. The gene discussed is TLR2; the disease is periodontitis.