TLR2 and periodontitis: Three studies derived from Caucasian ethnic involved 1596 cases and 1866 controls report the gene and showed that TLR-2 rs5734704 polymorphism might not contribute to periodontitis risk under all comparison models (p = 0.783, OR = 0.966, 95% CI: 0.755-1.237) either in Caucasian or disease study (p = 0.748, OR = 1.053, 95% CI: 0.770-1.439) (Figure 4 and Table 4).