Significant association was found between periodontitis and TLR-2 rs1898830 polymorphism under the allelic model (A allele vs. G allele: p = 0.014, OR = 1.208, 95% CI: 1.039-1.406), recessive model (GG vs. GA+AA: p = 0.028, OR = 0.755, 95% CI: 0.588-0.970), and codominant model (GG VS. Here, TLR2 is linked to periodontitis.