There was no significant difference in the baseline level between the two groups, including gender, age, combined disease (including hypertension, diabetes, and hyperlipidemia), blood lipids test (total cholesterol, glycerol triglyceride, and low-density lipoprotein), fasting blood glucose, electrocardiogram, BNP, the 6-minute walk test, and the Brog sensory score (Table 1, p > 0.05). The gene discussed is NPPB; the disease is diabetes mellitus.