Given that (a) our results show that p33ING1b expression is correlated to acetylation of p53 in the tested OSCC cell lines irrespective of their mutation status, (b) gain-of-function p53 mutation favors cancer progression unlike wild type p53, and (c) our observation that OSCC cell lines with mutated p53 have relatively high basal levels of acetylated p53 expression, it will be important to investigate how OSCC cell lines with mutant p53 circumvent the pro-apoptotic functions of increased acetylated p53. Here, TP53 is linked to cancer.