CD8A and Huntington disease: In contrast, the frequency of CD4+ and CD8+ (CCR7−CD45RA−) effector memory T cells was high on day 14 (51.7 and 28.6%, respectively) relative to that of HD (28.2% [21.8–29.4] and 23.5% [11–26], for CD4+ and CD8+ T cells, respectively) and peaked at day 24 (67.4% and 46.2%, respectively) (Fig. 2a).