Activated glia express TrkC.T1 mRNA at the onset of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) (Brahimi et al., 2016), glaucoma (Bai et al., 2010), and retinitis pigmentosa (Galan et al., 2017). The gene discussed is NTRK3; the disease is amyotrophic lateral sclerosis.