After adjustments for sex, ethnicity, social class and BMI, PRS-T2DM was associated with CRP (β = 0.03; 95% CI, 0.01–0.08, p = .040), but not with IL-6 (β = 0.01; 95% CI, −0.02–0.05, p = .082). This evidence concerns the gene IL6 and type 2 diabetes mellitus.