This observation is consistent with previous data from individuals with type 2 diabetes treated with an SGLT2 inhibitor [1, 2], as well as from transplant recipients who retained their native kidneys, and with clinical observations made in normal-glucose-tolerant individuals with familial renal glucosuria in whom normal fasting plasma glucose levels were maintained despite markedly elevated rates of urinary glucose excretion [13, 14]. Here, SLC5A2 is linked to type 2 diabetes mellitus.