MRI findings of anti-LGI1 encephalitis generally show abnormal FLAIR intensity in the hippocampus and medial temporal lobe which may be unilateral or bilateral while CSF findings are mostly normal with some cases showing oligoclonal bands.2,10,11 The illustrated case showed FLAIR intensity signal in bilateral temporal lobes with signal changes in the bilateral insular cortex. This evidence concerns the gene LGI1 and encephalitis.