ESR1 and breast neoplasm: In both cohorts examined, SLC2A1 mRNA expression is significantly elevated in basal-like subtype (corresponding to the most common subtype of TNBC11) compared to estrogen receptor positive and HER2-amplified breast tumors (TCGA: p = 3.33e−11; METABRIC: p = 2.53e−8) (Fig. 1a, b).