For instance, lncRNA PTAR as a ceRNA for the miR-101-3p regulates ZEB1 expression to promotes EMT and invasion-metastasis in ovarian cancer32, lncRNA- KRTAP5-AS1 and lncRNA-TUBB2A act as ceRNAs for miR-34 and miR-449 to facilitate CLDN4 expression and consequently promote gastric cancer cell proliferation and EMT process33. The gene discussed is CLDN4; the disease is gastric cancer.