In people using CFTR modulators and consequent systemic improvement in their CFTR function (leading to improvements in nutritional status, and possibly improving cervical mucus consistency and pH) [30], there have been reports of both improved fertility (7/12 women who previously reported infertility became pregnant with an average time to conception, following ivacaftor initiation of 3.2 months [range 1–8.5]) and unplanned pregnancies [39,40,41]. Here, CFTR is linked to Infertility.