In order to determine the potential role of the CXCR4-LASP1 axis and other proteins such as A20 in the regulation of the Snail1 stability, we screened several human luminal and basal breast cancer cell lines, for the protein levels of CXCR4, LASP1, LSD1, GSK-3β, Snail1 and A20 by the immunoblot analysis of total cell lysates. The gene discussed is GSK3B; the disease is breast cancer.