Yan et al. [269] reported that MB anthocyanins alleviated hypoglycemia by inhibiting ROS generation, promoting AMPK phosphorylation, activating tuberous sclerosis 2, (reducing the mTOR and ACC signaling), reducing p38-MAPK and PGC-1α expression, and increasing mitochondria and matrix metalloprotease (MMP) abundance in diabetic mice (Table 1) [97]. The gene discussed is PRKAA1; the disease is Hypoglycemia.