OGG1 and early-onset autosomal dominant Alzheimer disease: Alzheimer’s disease (AD) has been correlated to a reduced expression of the GirK2, GirK3, GirK4, KCNQ2, and KCNQ3 subunits and genes encoding for the antioxidants SOD, 8-oxoguanine DNA glycosylase (OGG1), and monoamine oxidase A (MAO-A) in rats [184].