As expected, we detected an upregulation of one major pro-apoptotic pathway involving Fas (C)/FADD(B) signaling, two other proteins which can promote apoptosis (p27/Kip1 (A); HIF-1α (D)), and two anti-apoptotic molecules (HMOX2 (E); Livin (F)) in CD4+ T cells derived from patients with septic shock compared to controls. Here, CD4 is linked to septic shock.