These immune cells include antigen-presenting dendritic cells (DCs), cytotoxic CD8+ T lymphocytes (CTLs), natural killer (NK) cells, type 1 and type 2 CD4+ T helper cells (Th1 and Th2), CD4+ regulatory T cells (Tregs), B lymphocytes, M1- and M2-like tumour-associated macrophages (TAMs), tumour-associated neutrophils (TANs), and myeloid-derived suppressor cells (MDSCs). This evidence concerns the gene CD8A and neoplasm.