To determine whether miR-26b-5p and miR-21-3p, selectively co-purified with the TAP1 3′ UTR, regulate the TAP1 expression via binding to TAP1 3′ UTR, the respective miR mimics and NC were transiently transfected into the melanoma cell lines BUF1379, FM3 and FM81. This evidence concerns the gene TAP1 and melanoma.