Huang et al. conducted a study, in which patients with severe infections, admitted to the intensive care unit, had elevated levels of plasma pro-inflammatory cytokines like IL2, IL10, IL7, granulocyte colony-stimulating factor (GSCF), interferon γ-induced protein (IP10), monocyte chemoattractant protein-1 (MCP1), macrophage inflammatory protein-1-α (MIP1A) and tumor necrosis factor α (TNFα). The gene discussed is TNF; the disease is infection.