CYB5R2 and nasopharyngeal carcinoma: The study found that combined analyses of 10 methylation markers (RASSF1A, DAPK, ITGA9, p16, WNT7A, CHFR, CYB5R2, WIF1, RIZ1, FSTL1) and two EBV markers (EBNA1 and LMP1) provided good discrimination between NPC and NPC control tissues with a detection rate of 91% in biopsies with 90% specificity [44].