In order to properly understand the role of the FLT3L/FLT3-complex in the course of MM, we analyzed FLT3 expression in bone marrow biopsies of patients with plasma cell dyscrasias (Table 1) by immunohistochemistry and real-time PCR and tested effects of FLT3 inhibitors on MM cell lines and on primary myeloma cells. This evidence concerns the gene FLT3LG and Miyoshi myopathy.