VEGFA and goiter: Comparisons between the groups revealed that VEGFA gene expression was higher in the goiter than in the tumor (RQ median = 20.28 vs. 1.5; p < 0.0001) and also in the goiter-adjacent tissue than in the tumor-adjacent tissue (RQ median = 20.72 vs. 3.40, p < 0.0001) (Figure 1).