We do know that upregulation of DRD1, DRD3, and DRD5 expression in blood, along with alterations in the expression of other dopaminergic signaling genes, has been associated with lower resilience to stressful events and other psychological parameters, including personality, depression, anxiety, and intelligence, in age, sex, and race-matched individuals [11]. This evidence concerns the gene DRD5 and Anxiety.