KRT20 and neoplasm: While no significant correlation between CK20 mRNA detection in blood and overall survival (p = 0.261) or tumor-specific survival (p = 0.196) could be determined in patients with early UICC stages, patients with late UICC stages (UICC III+IV) showed a higher 5-year overall survival when blood samples were tested CK20-negative than CK20-positive patients (Figure 4A).