Other stromal genes dysregulated in AA women with breast cancer include Ras association domain-containing protein 1 (RASSF1A), Retinoic acid receptor beta (Retinoic acid receptor beta), Spermatogenesis associated 18 (SPATA18), and Sons of sevenless drosophila homolog 1 (SOS1). The gene discussed is SOS1; the disease is breast carcinoma.