YBX1 and melanoma: A cross-detection of structurally related cold-shock proteins such as Y-box binding protein 3 (DbpA, P16989) in the melanoma cell culture supernatants can further be excluded, since Western blot analysis was performed with both antibodies targeting the C-terminus and the non-conserved N-terminus of YB-1 (Protein Accession: P67809) (Figure S1b).