YBX1 and melanoma: Correspondingly, we can show here not only that decreased amounts of intracellular YB-1 go along with its reduced extracellular occurrence (Figure S10c,d), but also that the melanoma cell lines used in the above mentioned previous studies (A375, 1205LU, SKMel28) [17,20] exhibit a robust intrinsic YB-1 secretion (Figure 1).