YBX1 and melanoma: As suggested by the absent impact of YB-1 knockdown on wound closure in melanoma cell lines lacking a substantial YB-1 secretion (SbCl2, WM793; Figure 1, Figure 5a; Figure S9a), the presence of an effect correlates with the intrinsic secretory capacity of YB-1 in the different melanoma cells (SbCl2, WM793 < WM266-4 < WM115, MelJuso, A375), which in turn hints to an involvement of extracellularly occurring YB-1.