Univariate analysis showed that patients with SRC were younger and more likely to be female and had more tumors located in the middle stomach, more scirrhous stromal reaction, a more infiltrating type, fewer microsatellite instability-high (MSI-H) tumors, more PIK3CA amplifications, less PD-L1 expression, fewer PI3K/AKT pathway mutations and more advanced Tumor, Node, Metastasis (TNM) stages than those without SRC. This evidence concerns the gene PIK3CA and neoplasm.