In our current study, we evaluated the neuroprotective effects of pretreated PYC originating from the maritime pine bark in the CA1 area of gerbil hippocampus following TFI using histochemistry with CV, immunohistochemistry with NeuN, and histofluorescence with F-J B. It was reported that PYC protected neuronal pheochromocytoma (PC)12 cells from hydrogen peroxide-induced injury in vitro [37]. The gene discussed is RBFOX3; the disease is pheochromocytoma.