MAPT and early-onset autosomal dominant Alzheimer disease: It is also known that heparin can induce the fibrillation of, for example, Tau [66], a protein involved in Alzheimer’s disease; transthyretin [67]; and non-amyloidogenic proteins [68], with different hypotheses for the heparin’s mode of action, one of which is as a scaffold for fibril formation, supporting fibril core structures.