In addition, this approach helped in characterizing the genetic basis shared by NAFLD with other liver diseases as well as with other metabolic disorders, by identifying a role for variants in membrane bound O-acyltransferase domain-containing 7 (MBOAT7) [56,57,58], IFNL3/IFNL4 [59,60] and FNDC5 in NAFLD [61]. Here, FNDC5 is linked to metabolic dysfunction-associated steatotic liver disease.