Of these, the expression of ZKSCAN3 was indeed significantly up-regulated in non-neoplastic prostate tissues from 24-week-old C57BL/6 mice undergoing vasectomy at 10 weeks (Figure 2B) and in prostate cancers from 24-week-old TRAMP mice undergoing vasectomy at 4 weeks (Figure 2C). Here, ZKSCAN3 is linked to Familial prostate cancer.