SYK and infection: Figure 7 shows that, upon adding DHA + P505-15 (2 nM + 250 nM) at different stages of parasite development, the maximal activity was observed between 12 and 36 h post infection corresponding to ring and trophozoite stages. The data in Figure 8B reveal that none of the drugs have a measurable impact on pRBC morphology at 6 h post infection, after which the monotherapies (i.e., DHA or Syk inhibitor alone) display detectable but comparatively mild effects (few pycnotic cells (less than 2%)) on pRBC morphology.