In this study, examining 7682 non-CKD and 970 patients with CKD stage 1–5, hs-cTnT and NT-proBNP were associated with the development of CV events (defined as the composite of coronary heart disease, stroke, and HF) independently of kidney measures (eGFR and albuminuria) [61]. The gene discussed is NPPB; the disease is hydrops fetalis.