PRF1 and tuberculosis: Whereas the median perforin levels after H37Ra stimulation were increased in both TB (before treatment, 404 pg/mL; after treatment, 440 pg/mL, p = 0.912, Figure 2c) and HIV/TB coinfection (before treatment, 391 pg/mL; after treatment, 498 pg/mL, p = 0.593, Figure 2d).