These results are agreeable with the findings previously shown of circulating IFN-γ and granulysin before and after completion of treatment [31], as well as the correlation of granulysin and cellular IFN-γ production with curative host responses in pulmonary TB, pointing to the potential role of granulysin, beside IFN-γ, in defense mechanisms in adults and children [32]. Here, IFNG is linked to pulmonary tuberculosis.