After 8 h, the S2VP10 orthotopic model indicated that tumor accumulation was 17.7 a.u, liver 5.7 a.u., and kidney 2.7 a.u. Similarly, SDC1-Lip-IR780 delivery in the S2CP9 orthotopic model indicated that tumor accumulation was 17.0 a.u, liver 1.5 a.u., and kidney 0.5 a.u. (Figure 5). The gene discussed is SDC1; the disease is neoplasm.