It is reported that there is an increased risk of ER- breast cancer (OR = 2.09; 95% CI = 1.19–3.67) in patients carrying the A allele for SNP rs743554, which is the predicted miRNA binding site for ITGB4. However, it should be noted that the status of HER2 is not included in this study; therefore, associations with TNBC could not be determined [72]. This evidence concerns the gene ERBB2 and breast carcinoma.