EGFR and non-small cell lung carcinoma: In particular, EGFR testing by liquid biopsy for patients with NSCLC has been approved in Europe based on the results of the IFUM trial (Iressa Follow-Up Measure; First-line gefitinib in Caucasian EGFR mutation-positive NSCLC patients: a phase- IV, open-label, single-arm study), which showed an acceptable sensitivity and specificity for this approach [7,10].