A high expression of ANXA8 represents a poor prognosis of overall survival and disease-free survival, and significantly correlates with the TNM (T for the size of the tumor and any spread of cancer into nearby tissue, N for the spread of cancer to nearby lymph nodes, and M for metastasis) staging system that was created by the American Joint Committee on Cancer (AJCC) and the International Union Against Cancer (UICC). This evidence concerns the gene ANXA8 and cancer.