According to a study by Liu et al., curcumin exerts its anti-tumor activity by the inhibition of cell proliferation of MDA-MB-231 and BT-483 breast cancer cells, and invasion via downregulation of NF-κB, transcription of matrix metalloproteinases (MMPs)-1 and cyclin D, a cell cycle regulatory protein [38] (Table 1). The gene discussed is NFKB1; the disease is breast cancer.