In a case-control study of 589 incident cases and 563 population-based controls conducted among Asian-American women, Wu et al. observed that the consumption of green tea was significantly related to decreased breast cancer risk (adjusted OR = 0.48; 95% CI: 0.29–0.77) among those who possess low activity COMT allele compared with nondrinkers. Here, COMT is linked to breast carcinoma.