Two scientific aspects are interesting in the study of interleukin 23 and its receptor: first, IL23 preferentially drives the developing Th17 cells into the highly inflammatory pathogenic subtype and has been associated with active Vogt‒Koyonagi‒Harada and Behçet’s uveitis [69,70]; and second, IL23R polymorphisms could be one of the factors involved in the complex interactions between smoking and the risk of developing sarcoidosis, a subject of controversy as studies show a reduction in the morbid risk in smokers [71]. Here, IL37 is linked to sarcoidosis.