PTGS2 and hepatocellular carcinoma: The anti-inflammatory effect in the sciatic nerve chronic constriction injury (CCI)-induced neuropathic pain model [51] and anticancer effect in the hepatocellular carcinoma (HCC) animal model [57] are reported to be caused by RosA, which regulates the expression of TNF-α, COX-2, IL-1β, and p65.